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DOWLOAD THE FINAL PROGRAM

Schedule

 

 

February 19th, 2020

9:00-10:45

Registration + Coffee

10:45-11:00

GEQB – Opening

Mario Delgado, IPBLN-CSIC, Granada, Spain

Juan Carlos Morales, IPBLN-CSIC, Granada, Spain 

11:00-13:30

Session 1

Chair: Juan Carlos Morales

 

11:00-11:45

Plenary Lecture (sponsored by “Molecules”, MDPI)

A chemistry-based multidisciplinary strategy to semi-synthetic glycovaccines: from concept to first-in-human study and more in the context of Shigella

Laurence A. Mulard, Institute Pasteur, France

               

11:45-12:15

Invited Lecture

Impact of Biophysical Techniques on Drug Discovery

Juan Félix Espinosa, Lilly, Madrid, Spain

 

12:15-12:45

Invited Lecture

Turning stem cells into a medicine

Mario Delgado, IPBLN-CSIC, Granada, Spain

 

12:45-13:15

Oral Communications

OC1. Glycodendropeptides as potential synthetic vaccines against allergy

Javier Rojo, IIQ-CSIC, Seville, Spain

OC2. Development of new streamlined saponin vaccine adjuvants: molecular-level insights into saponin conformation correlating with adjuvant activity

Alberto Fernández-Tejada, Cicbiogune, Bilbao, Spain

 

13:15-13:30

Flash Communications

FC1. Pablo Valverde, NMR Studies of the specific interaction of DC-SIGN with the blood group A/B antigens

FC2. Beatriz Fernández de Toro, Avenues to characterize the interactions of extended N-glycans with proteins by NMR spectroscopy: the influenza hemagglutinin case

FC3. Manuel González Cuesta, Enzyme regulators with self-delivery capabilities

13:30-15:00

Lunch 

15:00-16:30

Session 2

Chair: Rosario Sánchez Martín

 

15:00-15:30

Invited Lecture

Multi-Scale Approaches to Computer-Assisted Enzyme Design

Gonzalo Jiménez-Oses, CICBiogune, Bilbao, Spain

               

15:30-16:00

Invited Lecture

Efficient and Sustainable Synthesis of Muramic and Glucuronic acid Glycodendrimers as Dengue Virus Antagonists 

María José Hernáiz Gómez, Universidad Complutense, Madrid, Spain

 

16:00-16:15

Oral Communication

OC3. sp2-Iminosugar glycolipid mimetics as immunoregulatory agents

Elena M. Sánchez, University of Seville, Spain

                              

16:15-16:30

Flash Communications

FC4. Alejandra Matamoros Recio, Computational approaches to the structure and activation mechanism of Toll-like receptor 4

FC5. José Antonio Laz-Ruiz, TDesign and development of novel nanodevices for biomedical applications

FC6. María Pia Lenza, Deciphering the N-glycan profile and interactions of FcɛRIα by NMR

 

16:30-17:00

Coffee break + Poster session 1

17:00-18:30

Session 3

Chair: Ignacio Alfonso

 

17:00-17:30

Invited Lecture

Designing the 3D microenvironment of cells for the bioengineering of humanized tissues

Joao Mano, University of Aveiro, Portugal

               

17:30-18:00

Invited Lecture

Discovery of Novel Spirocycles as Inhibitors of the Mitochondrial Permeability Transition Pore Opening for the Treatment of Myocardial Reperfusion Injury

Delia Preti, University of Ferrara, Italy

 

18:00-18:15

Oral Communication

OC4. Interaction of amyloid-β with functionalised gold nanoparticles

Patrick Gámez, University of Barcelona, Spain

 

 

18:15-18:30

Flash Communications

FC7. Reyes Núnez Franco, Computational prediction of activity-enhancing mutations by allosteric networks optimization

FC8. María Dolores Moya Garzón, Development of salicylate derivatives with double GO/LDHA inhibitory activity as pharmacological approach for the treatment of primary hyperoxaluria type 1

FC9. Marta Pazo Pascual, Lipid responsive helical oligoalanines for cell penetration

 

18:30-19:00

Meeting - GEQB

 

 

February 20th, 2020

9:00-11:00

Session 4

Chair: José Luis Mascareñas

 

9:00-9:45

Plenary Lecture (sponsored by “Pharmaceuticals”, MDPI)

The Chemistry-medicine continuum: approaches to HIV/AIDS eradication and to enhanced immuno-therapy

 Paul Wender, Stanford University, USA   

               

9:45-10:15

Invited Lecture

To be announced
María Jesús Vicent, Centro de Investigación Príncipe Felipe, Valencia, Spain

 

10:15-10:45

Invited Lecture

Structural studies of weak protein-ligand complexes by NMR: novel saturation transfer difference (STD) NMR approaches

Jesús Angulo, Universidad de Sevilla, Spain

                              

10:45-11:00

Flash Communications

FC10. Javier Valverde Pozo, A fluorescence ICT sensor for aminopeptidase detection in live cells

FC11. Joan Miguel-Ávila, Transition Metal Promoted Cycloadditions in Biologic Media

FC12. Esther Jiménez Moreno, Acetals as acid-sensitive clevable linkers for the design of antibody-drug conjugates

 

11:00-11:30

Coffee break + Poster session 1

11:30-13:30

Session 5

Chair: Maria Jesús Vicent

                              

11:30-12:00

Invited Lecture

Bio-inspired Materials Based on Simple Peptidic Derivatives

Beatriz Escuder, Universitat Jaume I, Castellón, Spain

               

12:00-12:30

Invited Lecture

Nature-inspired DNA-based nanodevices for diagnostic and drug-delivery applications

Francesco Ricci, University of Rome, Italy

                            

12:30-13:00

Invited Lecture (sponsored by SEQT)

Development of synthetic Toxin-Antitoxin-based therapeutic systems for cancer treatment

Guillermo de la Cueva, Bionand, Spain

 

13:00-13:30

Oral Communications

OC5. Chemo-Enzymatic Total Synthesis of Sorbicillinoid Natural Products

Anna Sib, IIQ-CSIC, Seville, Spain

OC6. Applying dynamic chemistry for miR-21 direct detection and quantification

Antonio Delgado-González, University of Granada, Spain

 

13:30-15:00

Lunch 

15:00-16:30

Session 6

Chair: Óscar Millet

 

15:00-15:30

Invited Lecture (Young Investigator GEQB Award)

Supramolecular Chemistry Synthesizing Artificial Biology

Javier Montenegro, CIQUS, Santiago de Compostela, Spain

 

15:30-16:15

Oral Communications

OC7. Dendrimers as a powerful tool in biomedicine. Applications in tissue regeneration processes and as biomarkers

Yolanda Vida, University of Málaga, Spain

OC8. Ruthenium-catalyzed redox isomerizations inside living cells

Christian Vidal, CIQUS, Santiago de Compostela, Spain

OC9. Fighting Resistances: Photoswitchable Antimicrobials Fully Operated under Visible Light

Xavier Just-Baringo, IRB, Barcelona, Spain

 

16:15-16:30

Flash Communications

FC13. Salvador Guardiola, Target-based de novo design of heterochiral cyclic peptides against the PD-1/PD-L1 interaction

FC14. Guillermo Bañuelos Sánchez, Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons

FC15. Raik Artschawager, Towards the chemo-enzymatic synthesis of a N-glycomimetic library for the targeting of human DC-SIGN

 

16:30-17:00

Coffee break + Poster session 2

17:00-18:30

Session 7

Chair: Ana Conejo

 

17:00-17:45

Oral Communications

OC10. Dynamic stereoselection of kinetically-inert DNA-binding metallopeptide cylinders

Miguel Vázquez-López, CIQUS, Santiago de Compostela, Spain

OC11. GaudiMM: Opening New Horizons in Molecular Modeling of Chemobiological Systems

Jean-Didier Maréchal, UAB, Barcelona, Spain

OC12. Quinolimide-based probes: New tools to study protein-protein interactions

 Juan Antonio González-Vera, University of Granada, Spain

 

17:45-18:30

Plenary Lecture

Size matters! Controlling the cellular microenvironment yields new insight into the inner working of cells

Wilhelm T. S. Huck, Radboud University, The Netherlands

 

20:30

Conference dinner

 

 

February 21st, 2020

9:00-11:00

Session 8

Chair: Sonsoles Martín Santamaria

                              

9:00-9:45

Plenary Lecture

Breaking the limits in understanding glycan recognition by NMR

Jesús Jiménez-Barbero, Cicbiogune, Bilbao, Spain

               

9:45-10:15

Invited Lecture

The design of mGlu2 NAMs for neuropsychiatric disorders and studies towards potential tracers for PET imaging

Michiel Van Gool, Janssen, Toledo, Spain

 

10:15-10:45

Invited Lecture

Conformational landscapes in enzyme design

Silvia Osuna, Universitat di Girona, Spain

                              

10:45-11:05

Flash Communications

FC16. Lucía Tapia, Efficient tyrosine trapping by the supramolecular protection from Src phosphorylation

FC17. Mantas Liutkus, Modular Artificial Light Harvesting Systems

 

11:00-11:30

Coffee break + Poster session 2

11:30-13:30

Session 9

Chair: Eugenio Vázquez

 

11:30-12:30

Oral Communications

OC13. Non-coding RNAs delivered by Magnetic and Gold Nanoparticles for the treatment of Uveal Melanoma

Álvaro Somoza, IMDEA, Madrid, Spain

OC14. G-quadruplex DNA Structures as Drug Targets for Small Molecules

Jorge González García, University of Valencia, Spain

OC15. Studying the Reaction Mechanism of Orotate Phosphoribosyltransferase by means of X-ray Crystallography and Computational Simulations

Maite Roca, Universitat Jaume I, Castellón, Spain

OC16. (Best PhD thesis GEQB Award)

To be announced

               

12:30-13:00

Invited Lecture

Bioorthogonal turn-on photosensitizers

Olalla Vázquez, Philipps-Universität Marburg, Germany

 

13:00-13:30

Invited Lecture

NMR and biosynthetic gene cluster analysis strategies for the determination of the structure and full absolute configuration of complex microbial natural products

Fernando Reyes, Fundación Medina, Granada, Spain

 

13:30-13:45

Closing remarks & Best GEQB Flash & Poster awards

13:45-15:00

Mini-Lunch